This great talk by Stuart Firestein says yes!!
“Ignorance has a lot of bad connotations [but] I mean a different kind of ignorance. I mean a kind of ignorance that’s less pejorative, a kind of ignorance that comes from a communal gap in our knowledge, something that’s just not there to be known or isn’t known well enough yet or we can’t make predictions from, the kind of ignorance that’s maybe best summed up in a statement by James Clerk Maxwell, perhaps the greatest physicist between Newton and Einstein, who said, “Thoroughly conscious ignorance is the prelude to every real advance in science.” I think it’s a wonderful idea: thoroughly conscious ignorance.
So I’d say the model we want to take is not that we start out kind of ignorant and we get some facts together and then we gain knowledge. It’s rather kind of the other way around, really. What do we use this knowledge for? What are we using this collection of facts for? We’re using it to make better ignorance, to come up with, if you will, higher-quality ignorance.”